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toxicology

  • Why are OEL/ADE monographs more expensive for natural health products?
  • In reviewing the OEL and ADE equations, I see that the lowest therapeutic dose was used as the point of departure rather than the NOEL (no observed effect level) or NOAEL (no observed adverse effect level)
  • ADEs for different routes
  • Do I need a dedicated facility for my highly potent active pharmaceutical ingredient?
  • What data is needed to prepare an occupational health categorization report?
  • Use of the TTC vs calculating an ADE
  • Are Affygility Solutions' toxicologists certified?
  • What is the procedure for OEL Fastrac updates?
  • MultiCASE Q&A
  • I want to learn to learn how to calculate ADEs myself?
  • Should I panic when an OEL or ADE changes?
  • Why do OEL Fastrac monographs not contain the "PDE Determination Strategy" summary sheet contained in the Annex? Does this make the monograph non-compliant?
  • Are health based exposure limits required for all products?
  • Relationship between minimum therapeutic dose vs. ADE
  • How do I apply an OEL Fastrac ADE to a veterinary ADE?
  • Rounding conventions of occupational exposure limits and health based exposure limits
  • How can I establish an ADE for an early stage compound?
  • Do OEL Fastrac monographs include the maximum daily dose (MDD)?
  • EuroTox or Society of Toxicology Corporate Memberships
  • Will the OEL be higher if I prohibit women in the work area?
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